Janina Lange

PhD student

Room 02.074

Center for Medical Physics and Technology
Biophysics Group
Henkestrasse 91
91052 Erlangen
Germany

tel : (+49) (0)9131-85-25609;
fax: (+49) (0)9131-85-25601
email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Projects

Pore size distributions in collagen networks (2011)

Thermal Noise Imaging: observing the topology of collagen networks (2012), cooperation with Prof. E.-L. Florin

Collective cell migration (2012-2013), cooperation with PD Pamela Strissel, PhD

Cell rheology measurements with microfluidic devices (2013-...), cooperation with Prof. Graeme Whyte

 

Curriculum Vitae

FAU Erlangen-Nuremberg:

Physics (B.Sc.) , 2011

Physics (M.Sc.) ,  2013

PhD, (2013-...)

 

Conferences

Physics of Cancer (3rd Annual Meeting), Leipzig, Germany, 2012/11/01-2012/11/03

Janina R. Lange, Claus Metzner, Julian Steinwachs, Pamela Strissel, Ben Fabry

3D topology of tumor cell colonies on a 2D substrate

 

Biophysical Society 57th Meeting, Philadelphia, USA, 2013/02/02-2013/02/06

Tobias F. Bartsch, Martin D. Kochanczyk, Janina R. Lange, Ernst-Ludwig Florin

Three-dimensional thermal noise imaging of collagen networks

 

Annual Meeting of the German Physical Society (DPG), Regensburg, Germany,  2013/03/11-2013/03/15

Janina R. Lange, Claus Metzner, Patrick Krauss, Pamela Strissel, Ben Fabry

The role of collective cell migration during tumor growth

Patrick Krauss, Claus Metzner, Janina Lange, Ben Fabry

Persistent motion in the crowd - the role of superdiffusivity in cell colony dynamics

 

Physics of Emergent Behavior (IOP), Brighton, GB, 2013/06/23-2013/06/26:

Janina R. Lange, Claus Metzner, Patrick Krauss, Pamela Strissel, Ben Fabry

Collective migration during the growth of epithelial and mesenchymal cell colonies

Poster Prize

Patrick Krauss, Claus Metzner, Janina R. Lange, Ben Fabry

Emergence of cell colony dynamics from proliferating particles with Lennard-Jones like interactions

 

5th European Cell Mechanics Meeting, Obergurgel, Austria, 2013/09/28-2013/10/02:

Janina R. Lange, Claus Metzner, Patrick Krauss, Pamela Strissel, Ben Fabry

Collective Migration during the Growth of mesenchymal and epithelial cell colonies

 

Biophysical Society 58th Meeting, San Francisco, USA, 2014/02/15-2014/02/19:

Janina R. Lange, Michael Haug, Thorsten Kolb, Sahradha Albert, Graeme Whyte, Ben Fabry

Nuclear deformability is critically dependent on Lamin A/B

 

Physics of Cancer, (5rd Annual Meeting), Leipzig, Germany, 2014/10/02-2014/10/05:

Janina R. Lange, Thorsten Kolb, Jonas Hallmen, Graeme Whyte, Ben Fabry

Cell deformability during passage through micron-scale constrictions

 

6th European Cell Mechanics Meeting, Barcelona, Spain, 2015/05/13-2015/05/15:

Janina R. Lange, Julian Steinwachs, Thorsten Kolb, Lena A. Lautscham, Irina Harder, Graeme Whyte, Ben Fabry

Microconstriction arrays for high throughput quantitative measurements of cell mechanical properties

 

Biophysical Society 60th Meeting, Los Angeles, USA, 2016/02/27-2016/03/02:

Janina R. Lange, Julian Steinwachs, Claus Metzner, Graeme Whyte, Ben Fabry

Cell mechanical properties measured with micron-scale constrictions: influence of pressure, strain, and culture conditions

 

Annual meeting of the German biophysical society, Erlangen, Germany, 2016/10/04-2016/10/06:

Janina R. Lange, Claus Metzner, Sebastian Richter, Werner Schneider, Monika Spermann, Thorsten Kolb, Graeme Whyte, Ben Fabry

Unbiased high precision cell mechanical measurements with microconstrictions

 

Physics of Cancer, (7th Annual Meeting), Leipzig, Germany, 2016/10/04-2016/10/06:

Janina R. Lange, Claus Metzner, Sebastian Richter, Werner Schneider, Monika Spermann, Thorsten Kolb, Graeme Whyte, Ben Fabry

Unbiased high precision cell mechanical measurements with microconstrictions

 

 

Publications

Krauss P., Metzer C., Lange J.R., Lang N., Fabry B.
Parameter-Free Binarization and Skeletonization of Fiber Networks from Confocal Image Stacks
PLoS ONE 7:e36575, 2012 (PDF)

 

Lange J.R., Fabry B.

Cell and tissue mechanics in cell migration

Exp Cell Res 319: 2418–2423, 2013 (PDF)

 

Lange J.R., Auernheimer V., Strissel P., Goldmann W.H.

Influence of focal adhesion kinase on the mechanical behavior of cell populations

BBRC 436: 246-251, 2013 (PDF)

 

Lang N., Münster S., Metzner C., Krauss P., Lange J.R., Schürmann S., Aifantis K.E., Friedrich O, Fabry B.

Estimating the 3D pore size distribution of biopolymer networks from directionally biased data

Biophys. J. 105: 1967-1975, 2013 (PDF)

 

Lange, J.R., Steinwachs, J. Kolb, T. Lautscham, L.A., Harder, I. Whyte, G., Fabry, B.

Microconstriction arrays for high-throughput quantitative measurements of cell mechanical properties

 Biophys J. 109: 26–34, 2015 (PDF)

 

Lautscham L.A., Kämmerer C., Lange J.R., Kolb T., Mark C., Schilling A., Strissel P., Strick R., Gluth C., Rowat A., Metzner C., Fabry B.

Mechanical cell properties that influence migration in confined 3D environments

Biophys J 109:900-913, 2015 (PDF)

 

Bartsch T.F., Kochanczyk M.D., Lissek E.N., Lange J.R., Florin E.-L.

Nanoscopic imaging of thick heterogeneous soft-matter structures in aqueous solution

Nat. Commun. 7:12729 doi: 10.1038/ncomms12729,  2016 (PDF)

 

Lange J.R., Goldmann, W.H., Alonso J.L.

Influence of αvβ3 integrin on the mechanical properties and the morphology of M21 and K562 cells

BBRC (2016), 478:1280-5 (PDF)

 

Lange J.R., Metzner C., Richter S., Schneider W. Spermann M.,  Kolb T., Whyte G., Fabry B.

Unbiased high precision cell mechanical measurements with  microconstrictions

Biophys J , in press (PDF)